Amith Zafal Abdulla
HFSP Postdoctoral Fellow · Brandeis University
I'm a researcher at Brandeis University in the Boston area. My work explores the dynamics of epigenetic states at the single-cell level — blending molecular biology with computational modeling. I build computational models to gain deeper understanding of the processes that drive chromatin folding and gene regulation.
From modeling chromatin to collective behavior in active matter, I'm fascinated by the physics of biological systems.
I'd love to connect with people who can challenge me with new ways of thinking. If you're interested in theoretical models of how epigenetic patterns allow DNA to artfully change its expression, have a look at Painters in chromatin — or, if you prefer a short talk, here is a video.
To explore one of my latest projects, see the epigenetic oscillator, joint work with Jane Kondev and Kaushik Ragunathan.
Selected Publications
- Topological constraints and finite-size effects in quantitative polymer models of chromatin organization
- 4D epigenomics: deciphering the coupling between genome folding and epigenomic regulation with biophysical modeling
- Painters in chromatin: a unified quantitative framework to characterize epigenome regulation and memory
- Dynamical modeling of the H3K27 epigenetic landscape in mouse embryonic stem cells
- Contact force mediated rapid deposition of colloidal microspheres flowing over microstructured barriers
- Swimming statistics of cargo-loaded single bacteria
- Active modulation of surfactant-driven flow instabilities by swarming bacteria
- Tuning the torque–speed characteristics of the bacterial flagellar motor to enhance swimming speed
Contact
In life as in chromatin, it's the connections that matter...
415 South Street, Waltham MA 02453